Posted by: Indonesian Children | August 15, 2009

Pregnancy outcomes in young women with perinatally acquired human immunodeficiency virus-1.

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Pregnancy outcomes in young women with perinatally acquired human immunodeficiency virus-1.
Research

American Journal of Obstetrics & Gynecology. 200(2):149e1-149e5, February 2009.
Williams, Shauna F. MD a,*; Keane-Tarchichi, Megan H. MD a; Bettica, Linda RN b; Dieudonne, Arry MD b; Bardeguez, Arlene D. MD, MPH a

Abstract:
Objective: The objective of the study was to review pregnancy and neonatal outcomes among perinatally infected pregnant patients at our institution.

Study Design: A retrospective review of maternal and neonatal records for all 10 perinatally infected adolescents between 1997 and 2007 was performed. Demographics, CD4 and viral load, antiretroviral treatment, medical comorbidities, pregnancy outcomes, and neonatal human immunodeficiency virus (HIV) status were abstracted.

Results: The median age at first pregnancy was 18.5 years and 70% were African American. The most common comorbidities were hematologic abnormalities (70%) and cervical dysplasia/sexually transmitted infections (STIs) (80%). Initial median CD4 and viral load were 317 cells/mm3 and 8780 copies/mL, respectively. The median gestational age at delivery was 38 weeks. The most common obstetrical complications were preeclampsia (23%) and premature rupture of membranes/preterm delivery (31%). The cesarean delivery (CD) rate was 62%, with HIV as the indication in 75%. All infants were born alive; 1 was HIV infected.

Conclusion: Despite high rates of STIs, CD, preterm delivery, and hypertensive disorders, perinatal outcomes were favorable.

 

Supported by

FIGHT AGAINST  AIDS, SAVE  INDONESIAN CHILDREN

YUDHASMARA FOUNDATION

JL TAMAN BENDUNGAN ASAHAN 5 JAKARTA PUSAT, JAKARTA INDONESIA 10210

PHONE :62 (021) 70081995 – 5703646

Email : judarwanto@gmail.com 

https://childrenhivaids.wordpress.com/

 

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO

email : judarwanto@gmail.com,

 

Copyright © 2009,  FIGHT AGAINST  AIDS, SAVE  INDONESIAN CHILDREN  Information Education Network. All rights reserved.


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